Studies
Each Tolcylen product is developed with a strong commitment to scientific validation. In collaboration with leading physicians in clinical practice and respected researchers in laboratory settings, ongoing studies continue to evaluate the safety, efficacy, and performance of the Tolcylen product line. Below is a selection of completed and ongoing research.
Studies mentioned are performed by physicians in a clinical setting but do not represent effectiveness of the product. All results are solely for research purposes.
Efficacy of Topical Antifungal Nail Solution Versus Topical Placebo Solution for the Treatment of Pedal Onychomycosis: A Randomized Controlled Trial
- D. Scot Malay DPM. MSCE, FACFAS
- Hye Kim DPM, AACFAS
- Peter Bregman DPM, ABFAS
55%
Mycological Cure
At 7 to 9 months, PAS testing70%
Clinical Cure
At 7 to 9 months
Early Clinical Results: Topical Antifungal/Cosmetic Solution for Treatment of Toenail Dystrophy
- Kris DiNucci DPM, FACFAS
- D. Scot Malay DPM. MSCE, FACFAS
- Hye Kim DPM, AACFAS
68%
Mycological cure at 6 months
Using PAS testing85%
Significant clinical improvement of nail at 6 months
Nails graded on shape, thickness, percentage involvement, and overall involvement
Early and Visible Improvements after Application of K101 in the Appearance of Nails Discoloured and Deformed by Onychomycosis
92%
patients with onychomycosis
see marked improvement in nail appearance within 8 weeks77%
patients with onychomycosis
see marked improvement in nail appearance within 2 weeks
HQ-20363 Surface Tension and Contact Angle Measurements
- Nanoscience Analytical, 2019
- Objective: Evaluate how close the solution polar/disperive forces are to the nail Surface Free Energy
1.73%
Polar
Compared to 1.6% Nail Surface Free Energy.98.4%
Dispersive
Compared to 98.4% Nail Surface Free Energy.